• HEK293 expressed
  • Endotoxin-free
  • Animal-component free

HumanKine® recombinant human VEGF165 protein

Activity

0.3-3.75 ng/mL EC50

Species Reactivity

human

Purity

>95%

Cat no : HZ-1038

Synonyms

L VEGFA, MVCD1, Vascular permeability factor, VEGF, VEGF A, VEGF165, VEGFA, VPF



Technical Specifications

GeneID 7422
Species Human
Expression HEK293
Activity 0.3-3.75 ng/mL EC50
Purity >95%
Endotoxin<1 EU/µg
Accession NumberP15692
Molecular Mass 45 kDa, homodimer, glycosylated
Formulation 1x PBS, See Certificate of Analysis for details
Species Reactivity human

Stability and Reconstitution

Stability and StorageProduct FormTemperature ConditionsStorage Time
(From Date of Receipt)
Lyophilized-20°C to -80°CUntil Expiry Date
LyophilizedRoom Temperature2 weeks
Reconstituted as per CofA-20°C to -80°C6 months
Reconstituted as per CofA4°C1 week
Avoid repeated freeze-thaw cycles.
Reconstitution Briefly centrifuge the vial before opening. It is recommended to reconstitute the protein in sterile 1xPBS pH 7.4 containing 0.1% endotoxin-free recombinant serum albumin (HSA).

Background

This gene is a member of the PDGF/VEGF growth factor family. It encodes a heparin-binding protein, which exists as a disulphide-linked homodimer (PMID 10838264; 11329058). This growth factor induces proliferation and migration of vascular endothelial cells and is essential for physiological and pathological angiogenesis. Misregulations of this gene in mice result in abnormal embryonic blood vessel formation.

Synonyms

L VEGFA, MVCD1, Vascular permeability factor, VEGF, VEGF A, VEGF165, VEGFA, VPF

Publications

SpeciesTitle
human

Nat Methods

Conversion of human fibroblasts to angioblast-like progenitor cells.

Authors - LeoKurian
human

Cell Res

Single-cell transcriptomic atlas of primate cardiopulmonary aging.

Authors - Shuai Ma
human

Circulation

Identification of novel long noncoding RNAs underlying vertebrate cardiovascular development.

Authors - LeoKurian
human

Cell Res

SIRT6 safeguards human mesenchymal stem cells from oxidative stress by coactivating NRF2.

Authors - HuizePan

Nat Commun

DutaFabs are engineered therapeutic Fab fragments that can bind two targets simultaneously.

Authors - Roland Beckmann
human

EMBO J

RhoJ integrates attractive and repulsive cues in directional migration of endothelial cells.

Authors - Yoko Fukushima