• Featured Product
  • KD/KO Validated

ALDH7A1 Polyclonal antibody

ALDH7A1 Polyclonal Antibody for IHC, WB, ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse, rat

Applications

WB, IHC, IF, ELISA

Conjugate

Unconjugated

Cat no : 10368-1-AP

Synonyms

ALDH7A1, Alpha AASA dehydrogenase, Antiquitin 1, ATQ1, Betaine aldehyde dehydrogenase, EPD, P6c dehydrogenase, PDE



Tested Applications

Positive WB detected inHepG2 cells, mouse kidney tissue, mouse liver tissue, HeLa cells
Positive IHC detected inhuman ovary tumor tissue
Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0

Recommended dilution

ApplicationDilution
Western Blot (WB)WB : 1:500-1:3000
Immunohistochemistry (IHC)IHC : 1:250-1:1000
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

Product Information

10368-1-AP targets ALDH7A1 in WB, IHC, IF, ELISA applications and shows reactivity with human, mouse, rat samples.

Tested Reactivity human, mouse, rat
Cited Reactivityhuman, mouse, rat
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen ALDH7A1 fusion protein Ag0383
Full Name aldehyde dehydrogenase 7 family, member A1
Calculated Molecular Weight 55 kDa
Observed Molecular Weight 55 kDa
GenBank Accession NumberBC002515
Gene Symbol ALDH7A1
Gene ID (NCBI) 501
RRIDAB_2242476
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. 20ul sizes contain 0.1% BSA.

Background Information

ALDH7A1(Alpha-aminoadipic semialdehyde dehydrogenase) is also named as ATQ1 and belongs to the aldehyde dehydrogenase family. It plays a major role in the detoxification of aldehydes generated by alcohol metabolism and lipid peroxidation. This protein has 4 isoforms produced by alternative splicing.

Protocols

Product Specific Protocols
WB protocol for ALDH7A1 antibody 10368-1-APDownload protocol
IHC protocol for ALDH7A1 antibody 10368-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols

Publications

SpeciesApplicationTitle
mouse, ratWB

Arch Toxicol

Protective effects of dioscin against alcohol-induced liver injury.

Authors - Xu Tingting T
ratWB

Food Funct

Correction: Total saponins from Rosa laevigata Michx fruit attenuates hepatic steatosis induced by high-fat diet in rats.

Authors - Deshi Dong
humanIHC,WB,IF

Exp Cell Res

EPS8 supports pancreatic cancer growth by inhibiting BMI1 mediated proteasomal degradation of ALDH7A1.

Authors - Mingzhu Tan
  • KD Validated
ratWB

PLoS One

Metabolomic mechanisms of gypenoside against liver fibrosis in rats: An integrative analysis of proteomics and metabolomics data.

Authors - Ya-Nan Song
ratWB

Food Funct

Total saponins from Rosa laevigata Michx fruit attenuates hepatic steatosis induced by high-fat diet in rats.

Authors - Deshi Dong

J Toxicol Sci

Mechanisms of CCl4-induced liver fibrosis with combined transcriptomic and proteomic analysis.

Authors - Shu Dong

Reviews

The reviews below have been submitted by verified Proteintech customers who received an incentive forproviding their feedback.


FH

Hua (Verified Customer) (12-04-2018)

  • Applications: Western Blot,
  • Primary Antibody Dilution: 1:1000
  • Cell Tissue Type: mouse liver, mouse hippocampus / HepG2
ALDH7A1 Antibody Western Blot, validation (1:1000 dilution) in mouse liver, mouse hippocampus / HepG2 (Cat no:10368-1-AP)