ANGPTL7 Antibody 1 Publications

Rabbit Polyclonal| Catalog number: 10396-1-AP

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Freight/Packing

Con: 25 μg/150 μl

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Species specificity:
human, mouse

Positive WB detected in:
MCF7 cells, COLO 320 cells, HepG2 cells, MCF-7 cells, Y79 cells

Recommended dilution:
WB : 1:500-1:1000

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.1% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
angiopoietin-like 7

Calculated molecular weight:
40 kDa

Observed molecular weight:
45 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
ANGPTL7

Synonyms
angiopoietin like 7, Angiopoietin like factor, Angiopoietin like protein 7, Angiopoietin related protein 7, ANGPTL7, AngX, CDT6, dJ647M16.1, RP4 647M16.2
Background

ANGPTL7, also named as CDT6, is a member of the angiopoietin-like (ANGPTL) family of proteins, which are important regulators of Angiogenesis. It is a secreted 45-kDa glycoprotein that folds into a homotetramer structure linked by disulfide bonds. ANGPTL7 was originally discovered in the stromal layer of the corne, and moderately expressed in the human trabecular meshwork. The chromosomal location of the ANGPTL7 gene (1p36.22) is within the GLC3B locus (1p36.2-1p36.1) of primary congenital glaucoma, supporting ANGPTL7 as a candidate glaucoma gene. ANGPTL7 could have a pathogenic role in glaucoma, and may serve as a potential therapeutic target.


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