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ANGPTL7 Antibody 1 Publications

Rabbit Polyclonal| Catalog number: 10396-1-AP

Featured Product KD/KO validated

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Con: 25 μg/150 μl

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Tested Applications

Applications:
WB, IF, ELISA
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ANGPTL7 Antibody WB MCF-7 cells 10396-1-AP

MCF7 cells were subjected to SDS PAGE followed by western blot with 10396-1-AP(ANGPTL7 antibody) at dilution of 1:800 incubated at room temperature for 1.5 hours

ANGPTL7 Antibody WB MCF-7 cells 10396-1-AP

WB result of ANGPTL7 antibody (10396-1-AP; 1:5000; incubated at room temperature for 1.5 hours) with sh-Control and sh-ANGPTL7 transfected MCF-7 cells

Species specificity:
human, mouse
Positive WB detected in:
MCF7 cells, COLO 320 cells, HepG2 cells, Y79 cells
Recommended dilution:
WB : 1:500-1:1000
Sample-dependent, check data in Validation tab

Protocols

Product-specific protocols

Standard Protocols

Product Information

Source:
Rabbit
Purification method:
Antigen affinity purification
Isotype:
IgG
Storage:
PBS with 0.1% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information

Immunogen:
ANGPTL7 fusion protein Ag0596
Full name:
angiopoietin-like 7
Calculated molecular weight:
40 kDa
Observed molecular weight:
45 kDa
GenBank accession number:
BC001881
Gene ID (NCBI):
10218
Gene symbol
ANGPTL7
Synonyms
angiopoietin like 7, Angiopoietin like factor, Angiopoietin like protein 7, Angiopoietin related protein 7, ANGPTL7, AngX, CDT6, RP4 647M16.2

Background

ANGPTL7, also named as CDT6, is a member of the angiopoietin-like (ANGPTL) family of proteins, which are important regulators of Angiogenesis. It is a secreted 45-kDa glycoprotein that folds into a homotetramer structure linked by disulfide bonds. ANGPTL7 was originally discovered in the stromal layer of the corne, and moderately expressed in the human trabecular meshwork. The chromosomal location of the ANGPTL7 gene (1p36.22) is within the GLC3B locus (1p36.2-1p36.1) of primary congenital glaucoma, supporting ANGPTL7 as a candidate glaucoma gene. ANGPTL7 could have a pathogenic role in glaucoma, and may serve as a potential therapeutic target.


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