RhoGDI Antibody 8 Publications

Rabbit Polyclonal| Catalog number: 10509-1-Ig

Featured Product KD/KO validated

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Freight/Packing

Con: 90 μg/150 μl

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Species specificity:
human, mouse, rat

Positive WB detected in:
Jurkat cells, A431 cells, HEK-293 cells, HeLa cells, HL-60 cells, mouse pancreas tissue

Positive IHC detected in:
human breast cancer tissue, human breast cancer tissue, human colon cancer tissue

Recommended dilution:
WB : 1:500-1:2000
IHC : 1:20-1:200

Product Information


Source:
Rabbit

Purification method:
Protein A purification

Isotype:
IgG

Storage:
PBS with 0.1% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
Rho GDP dissociation inhibitor (GDI) alpha

Calculated molecular weight:
28 kDa

Observed molecular weight:
28 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
ARHGDIA

Synonyms
aGDI, ARHGDIA, GDIA1, Rho GDI 1, Rho GDI alpha, RHOGDI, RHOGDI 1
Background

Aplysia Ras-related homologs (ARHs), also called Rho genes, belong to the RAS gene superfamily encoding small guanine nucleotide exchange (GTP/GDP) factors. The ARH proteins may be kept in the inactive, GDP-bound state by interaction with GDP dissociation inhibitors, such as ARHGDIA (also called Rho GDP-dissociation inhibitor 1, Rho GDI1). Rho GDI1 acts as a metastasis-related protein in colon and prostate cancer patients and may be useful as a diagnostic biomarker to prevent colon and prostate cancer metastasis.


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