ARHGDIB Antibody 0 Publications

Mouse Monoclonal| Catalog number: 66054-1-Ig |CloneNo.: 3E7B7

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Freight/Packing

Con: 151 μg/150 μl

Choose size:

Please visit your regions distributor:


Species specificity:
human

Positive WB detected in:
U937 cells, U-937 cells

Recommended dilution:
WB : 1:500-1:2000

Product Information


Source:
Mouse

Purification method:
Protein A purification

Isotype:
IgG2b

Storage:
PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
Rho GDP dissociation inhibitor (GDI) beta

Calculated molecular weight:
201aa,23 kDa

Observed molecular weight:
27 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
ARHGDIB

Synonyms
ARHGDIB, D4, GDIA2, GDID4, Ly GDI, LYGDI, RAP1GN1, Rho GDI 2, Rho GDI beta, RhoGDI2
Background

ARHGDIB, also known as RhoGDI2, is a conserved member of the RhoGDI family and plays an important role in cell migrations. It regulates the GDP/GTP exchange reaction of the Rho proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP to them. It is mainly in hematopoietic, endothelial, and epithelial cells. It has been linked to tumorigenesis and metastasis. RhoGDI2 expression is downregulated in several cancer types, such as bladder, lung and lymphoma, but is upregulated in prostate and gastric cancer.


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