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ARHGDIB Antibody 0 Publications

Mouse Monoclonal| Catalog number: 66054-1-Ig |CloneNo.: 3E7B7

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Con: 151 μg/150 μl

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Tested Applications
Applications:
ELISA, WB
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ARHGDIB Antibody WB U-937 cells 66054-1-Ig

U-937 cells were subjected to SDS PAGE followed by western blot with 66054-1-Ig(ARHGDIB antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours

Species specificity:
human
Positive WB detected in:
U937 cells, U-937 cells
Recommended dilution:
WB : 1:500-1:2000

Product Information

Source:
Mouse
Purification method:
Protein A purification
Isotype:
IgG2b
Storage:
PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information

Immunogen:
ARHGDIB fusion protein ag9091
Full name:
Rho GDP dissociation inhibitor (GDI) beta
Calculated molecular weight:
201aa,23 kDa
Observed molecular weight:
27 kDa
GenBank accession number:
BC009200
Gene ID (NCBI):
397
Gene symbol
ARHGDIB
Synonyms
ARHGDIB, D4, GDIA2, GDID4, Ly GDI, LYGDI, RAP1GN1, Rho GDI 2, Rho GDI beta, RhoGDI2
Background

ARHGDIB, also known as RhoGDI2, is a conserved member of the RhoGDI family and plays an important role in cell migrations. It regulates the GDP/GTP exchange reaction of the Rho proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP to them. It is mainly in hematopoietic, endothelial, and epithelial cells. It has been linked to tumorigenesis and metastasis. RhoGDI2 expression is downregulated in several cancer types, such as bladder, lung and lymphoma, but is upregulated in prostate and gastric cancer.


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