BTG1 Antibody 2 Publications

Rabbit Polyclonal| Catalog number: 14879-1-AP

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Con: 45 μg/150 μl

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Species specificity:
human, mouse, rat

Positive IHC detected in:
human lymphoma tissue

Recommended dilution:
IHC : 1:20-1:200

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
B-cell translocation gene 1, anti-proliferative

Calculated molecular weight:
19 kDa

Observed molecular weight:

GenBank accession number:

Gene ID (NCBI):

Gene symbol
BTG1

Synonyms
BTG1, Protein BTG1
Background

BTG1 is a member of the TOB/BTG family of proteins known to inhibit cell proliferation and negatively regulate the cell cycle (PMID: 25017022). It is strongly expressed in quiescent cells (maximal in the G0/G1 phase) and down-regulated as the cells enter the growth cycle (PMID: 1373383). BTG1 protein is localized in cytoplasm and nucleus, and can interact with CAF1 and PRMT1 (PMID: 1113675, 9712883, 26622543). The aberration of BTG1 expression is associated with B-cell lymphocytic leukemia, and may serve as a diagnostic indicator and prognostic marker of thyroid carcinoma (PMID: 2069907, 25017022).


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