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Caveolin-1 Antibody 9 Publications

Rabbit Polyclonal| Catalog number: 16447-1-AP

Featured Product KD/KO validated

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Con: 38 μg/150 μl

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Tested Applications
Applications:
ELISA, IF, IHC, IP, WB
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Images See all

16447-1-AP;HeLa cells

WB result of Caveolin-1 antibody (16447-1-AP, 1:3000) with si-Control and si-Caveolin-1 transfected HeLa cells.

16447-1-AP;A549 cells

A549 cells were subjected to SDS PAGE followed by western blot with 16447-1-AP( Caveolin-1 Antibody) at dilution of 1:600 incubated at room temperature for 1.5 hours

16447-1-AP;A549 cells

IP Result of anti-Caveolin-1 (IP:16447-1-AP, 3ug; Detection:16447-1-AP 1:500) with A549 cells lysate 1200ug.

16447-1-AP;human lung cancer tissue

Immunohistochemistry of paraffin-embedded human lung cancer tissue slide using 16447-1-AP( Caveolin-1 Antibody) at dilution of 1:200 (under 40x lens).

16447-1-AP;human lung cancer tissue

Immunohistochemistry of paraffin-embedded human lung cancer tissue slide using 16447-1-AP( Caveolin-1 Antibody) at dilution of 1:200 (under 10x lens).

Species specificity:
human, mouse, rat
Positive WB detected in:
A549 cells, HeLa
Positive IP detected in:
A549 cells
Positive IHC detected in:
human lung cancer tissue, human lung tissue, human heart tissue, human liver tissue
Recommended dilution:
WB : 1:500-1:1000
IP : 0.5-4.0 ug for IP and 1:500-1:1000 for WB
IHC : 1:50-1:500

Product Information

Source:
Rabbit
Purification method:
Antigen affinity purification
Isotype:
IgG
Storage:
PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information

Immunogen:
Caveolin-1 fusion protein Ag8049
Full name:
caveolin 1, caveolae protein, 22kDa
Calculated molecular weight:
22 kDa
Observed molecular weight:
20-25 kDa
GenBank accession number:
BC006432
Gene ID (NCBI):
857
Gene symbol
CAV1
Synonyms
BSCL3, CAV, CAV1, Caveolin 1, Caveolin-1, CGL3, MSTP085, VIP21
Background

Caveolin-1 (CAV1), a multifunctional protein, is the main constituent molecule of caveolae and represents a scaffolding molecule for several signaling molecules including epidermal growth factor receptor (PMID: 19641024). Several studies have implicated that a reduced expression of CAV1 was found in cancers including head and neck carcinoma (PMID: 19002186). However, other studies recognize CAV1 as a tumor promoter because CAV1 is overexpressed in various kinds of cancers, especially in oral cancer (PMID: 20558341). Recent study also show that CAV1 is involved in astric Cancer (PMID: 25339030).


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