CD33 Antibody 1 Publications

Rabbit Polyclonal| Catalog number: 17425-1-AP

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Freight/Packing

Con: 20 μg/150 μl

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Species specificity:
human

Positive WB detected in:
K-562 cells

Positive IHC detected in:
human spleen tissue, human brain tissue, human kidney tissue, human lung tissue, human ovary tissue, human placenta tissue, human spleen tissue, human testis tissue

Positive IF detected in:
HepG2 cells

Positive FC detected in:
U-937 cells

Recommended dilution:
WB : 1:500-1:1000
IHC : 1:20-1:200
IF : 1:10-1:100

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
CD33 molecule

Calculated molecular weight:
364aa,40 kDa

Observed molecular weight:
67 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
CD33

Synonyms
CD33, CD33 molecule, FLJ00391, gp67, p67, SIGLEC 3, SIGLEC3
Background

CD33, aslo referred to as Siglec-3, is a 67-kDa glycosylated transmembrane protein of sialic acid-binding immunoglobulin-like lactic (siglec) family. CD33 expression is restrict to cells of the hematopoietic system. It is expressed on monocytes, myeloid progenitors, granulocytes, mast cells, some T cells. This molecular may mediate cell-to-cell adhesion and act as receptor that inhibits the proliferation of normal and leukemic myeloid cells.


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