Chromogranin A Antibody 0 Publications

Mouse Monoclonal| Catalog number: 60135-1-Ig |CloneNo.: 3H11C11

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Freight/Packing

Con: 150 μg/150 μl

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Species specificity:
human, rat, pig, mouse

Positive WB detected in:
rat pancreas tissue, Transfected HEK-293 cells

Positive IHC detected in:
human pancreas tissue, human colon tissue

Positive IF detected in:
PC-12 cells

Recommended dilution:
WB : 1:1000-1:4000
IHC : 1:50-1:500
IF : 1:50-1:500

Product Information


Source:
Mouse

Purification method:
Protein G purification

Isotype:
IgG1

Storage:
PBS with 0.1% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
chromogranin A (parathyroid secretory protein 1)

Calculated molecular weight:
51 kDa

Observed molecular weight:
70 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
CHGA

Synonyms
CGA, CHGA, Chromogranin A, Pituitary secretory protein I, SP I, Vasostatin I Vasostatin 2
Background

Chromogranin A is a member of the granin family of neuroendocrine secretory proteins. It is located in secretory vesicles of neurons and endocrine cells. Chromogranin A is the precursor to several functional peptides including vasostatin, pancreastatin, catestatin and parastatin. These peptides negatively modulate the neuroendocrine function of the releasing cell (autocrine) or nearby cells (paracrine). CgA is one of the most used tumor markers in NET's (neuroendocrine tumors) , and elevated CgA concentrations have been demonstrated in serum or plasma of patients with different types of these tumors.


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