CHRNA3 Antibody 4 Publications

Rabbit Polyclonal| Catalog number: 10333-1-AP

Featured Product KD/KO validated

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Freight/Packing

Con: 15 μg/150 μl

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Species specificity:
human, mouse

Positive WB detected in:
mouse thymus tissue, A549 cells, HEK-293 cells, HepG2 cells, mouse brain tissue

Positive IHC detected in:
human prostate cancer tissue

Positive FC detected in:
SH-SY5Y cells

Recommended dilution:
WB : 1:500-1:1000
IHC : 1:20-1:200

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.1% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
cholinergic receptor, nicotinic, alpha 3

Calculated molecular weight:
57 kDa

Observed molecular weight:
50-55 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
CHRNA3

Synonyms
CHRNA3, LNCR2, NACHRA3, PAOD2
Background

CHRNA3, also named as NACHRA3, LNCR2 and PAOD2, is neuronal type nAChR subunits. It is a member of the nicotinic acetylcholine receptor family, which plays an important role in calcium regulation, neuronal development, and cognitive functions. Polymorphisms in this gene have been associated with an increased risk of smoking initiation and an increased susceptibility to lung cancer.


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