Claudin 1 Antibody 4 Publications

Rabbit Polyclonal| Catalog number: 13050-1-AP

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Freight/Packing

Con: 30 μg/150 μl

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Species specificity:
human, mouse, dog

Positive WB detected in:
mouse skin tissue, mouse liver tissue, mouse thymus tissue

Positive IHC detected in:
human skin tissue, human cervical cancer tissue, human liver tissue, human oesophagus cancer tissue, human skin tissue, human skin cancer tissue, mouse colon tissue

Positive IF detected in:
MDCK cells

Recommended dilution:
WB : 1:500-1:1000
IHC : 1:50-1:200
IF : 1:50-1:500

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
claudin 1

Calculated molecular weight:
211aa,23 kDa

Observed molecular weight:
23 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
CLDN1

Synonyms
claudin 1, CLD1, CLDN1, ILVASC, SEMP1
Background

Claudins are a family of proteins that are the most important components of the tight junctions, where they establish the paracellular barrier that controls the flow of molecules in the intercellular space between the cells of an epithelium. 23 claudins have been identified. They are small (20-27 kilodalton (kDa)) proteins with very similar structure. They have four transmembrane domains, with the N-terminus and the C-terminus in the cytoplasm. Claudin-1 is expressed primarily in keratinocytes and normal mammary epithelial cells.


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