DRP1 Antibody 5 Publications

Rabbit Polyclonal| Catalog number: 12957-1-AP

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Freight/Packing

Con: 24 μg/150 μl

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Species specificity:
human, mouse, monkey

Positive WB detected in:
mouse brain tissue, NIH/3T3 cells, Transfected HEK-293 cells

Positive IP detected in:
mouse brain tissue

Recommended dilution:
WB : 1:500-1:1000
IP : 0.5-4.0 ug for IP and 1:500-1:1000 for WB

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
dynamin 1-like

Calculated molecular weight:
710aa,79 kDa

Observed molecular weight:
75-80 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
DNM1L

Synonyms
DLP1, DNM1L, DRP1, DYMPLE
Background

DNM1L(Dynamin-1-like protein) , also known as dynamin-related protein 1 (DRP1), belongs to the dynamin family of large GTPases that mediate membrane remodeling during a variety of cellular processes. DNM1L has an important role in the division of growing mitochondria and peroxisomes and also mediates outer mitochondrial membrane fission in mammalian cells. DNM1L is ubiquitously expressed with abundant expression in skeletal muscle, heart, kidney and brain.Variable isoforms of DNM1L have been reported in a tissue-specific manner due to the alternative splicing.


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