EIF2AK2, PKR Antibody 1 Publications

Rabbit Polyclonal| Catalog number: 18244-1-AP

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Con: 32 μg/150 μl

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Species specificity:
human, mouse , rat

Positive WB detected in:
MCF7 cells, Jurkat cells, HeLa cells, mouse thymus tissue, rat heart tissue

Positive IP detected in:
HeLa cells

Positive IHC detected in:
human kidney tissue, human testis tissue, human heart tissue, human placenta tissue, human skin tissue, human brain tissue, human spleen tissue, human lung tissue, human ovary tissue

Positive IF detected in:
MCF-7 cells

Recommended dilution:
WB : 1:1000-1:4000
IP : 0.5-4.0 ug for IP and 1:500-1:1000 for WB
IHC : 1:50-1:500
IF : 1:10-1:100

Product Information


Purification method:
Antigen affinity purification


PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information

Full name:
eukaryotic translation initiation factor 2-alpha kinase 2

Calculated molecular weight:
551aa,62 kDa

Observed molecular weight:
65-68 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol

eIF 2A protein kinase 2, EIF2AK1, EIF2AK2, P1/eIF 2A protein kinase, p68 kinase, PKR, PRKR, Protein kinase RNA activated

The eukaryotic translation initiation factor 2-alpha kinase 2 (EIF2AK2, also known as PKR or PRKR) is an important component of the host innate immuneantiviral response.The product of the HSAEIF2AK2 gene is a 68 kDa protein that is ubiquitously expressed at low levels. The N-terminal part of this protein contains two dsRNA binding motifs (dsRBM) .The C-terminal EIF2S1 kinase domain includes 12 sub-domains that are conserved in several Species(PMID:16954046 ).This antibody is specific to EIF2AK2.

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