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  • KD/KO Validated

FABP3 Antibody

FABP3 Polyclonal Antibody for IF, IHC, WB, ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse, rat

Applications

WB, IHC, IF, ELISA

Conjugate

Unconjugated

Cat no : 10676-1-AP

Synonyms

FABP11, FABP3, Fatty acid binding protein 3, H FABP, HFABP, M FABP, MDGI, O FABP



Tested Applications

Positive WB detected inmouse heart tissue, HepG2 cells, human heart tissue, human skeletal muscle tissue, MCF-7 cells, mouse skeletal muscle tissue, rat testis tissue
Positive IHC detected inhuman breast cancer tissue, human heart tissue, human lung tissue, human ovary tissue, human placenta tissue, human skin tissue, human spleen tissue, human testis tissue
Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0
Positive IF detected inMCF-7 cells

Recommended dilution

ApplicationDilution
Western Blot (WB)WB : 1:500-1:2000
Immunohistochemistry (IHC)IHC : 1:20-1:200
Immunofluorescence (IF)IF : 1:50-1:500
Sample-dependent, check data in validation data gallery

Product Information

10676-1-AP targets FABP3 in WB, IHC, IF, ELISA applications and shows reactivity with human, mouse, rat samples.

Tested Reactivity human, mouse, rat
Cited Reactivity mouse
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen FABP3 fusion protein Ag1069
Full Name fatty acid binding protein 3, muscle and heart (mammary-derived growth inhibitor)
Calculated molecular weight 15 kDa
Observed molecular weight 15 kDa
GenBank accession number BC007021
Gene symbol FABP3
Gene ID (NCBI) 2170
Conjugate Unconjugated
Form Liquid
Purification Method Antigen affinity purification
Storage Buffer PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

Background Information

FABP3 (fatty-acid-binding protein 3), also known as heart-type FABP or mammary-derived growth inhibitor (MDGI), is a small 15-kDa cytoplasmic protein transporting fatty acids and other lipophilic substances from the cytoplasm to the nucleus. It is most ubiquitously expressed in heart and skeletal muscle.

Protocols

Product Specific Protocols
WB protocol for FABP3 antibody 10676-1-APDownload protocol
IHC protocol for FABP3 antibody 10676-1-APDownload protocol
IF protocol for FABP3 antibody 10676-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols

Publications

SpeciesApplicationTitle
mouseWB

Toxicology

Downregulations of placental fatty acid transporters during cadmium-induced fetal growth restriction.

Authors - Peng Xu
mouseWB

Cell Death Dis

Prohibitin 2 deficiency impairs cardiac fatty acid oxidation and causes heart failure.

Authors - Dechao Wu
mouseWB

Cell Death Discov

Malathion increases apoptotic cell death by inducing lysosomal membrane permeabilization in N2a neuroblastoma cells: a model for neurodegeneration in Alzheimer's disease.

Authors - Ramu Venkatesan
mouseWB,IF

Brain Res

Development of FABP3 ligands that inhibit arachidonic acid-induced α-synuclein oligomerization.

Authors - An Cheng
mouseWB

J Biol Chem

Aberrant fatty acid metabolism in skeletal muscle contributes to insulin resistance in zinc transporter 7 (Znt7)-knockout mice.

Authors - Liping Huang
mouseWB,IF

J Biol Chem

FABP3 promotes αSyn oligomerization associated with MPTP-induced neurotoxicity.

Authors - Norifumi Shioda
  • KO Validated