FGF12 Antibody 0 Publications

Rabbit Polyclonal| Catalog number: 13784-1-AP

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Freight/Packing

Con: 40 μg/150 μl

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Species specificity:
human, mouse

Positive WB detected in:
mouse brain tissue

Positive IP detected in:
mouse brain tissue,

Positive IHC detected in:
mouse brain tissue

Recommended dilution:
WB : 1:500-1:1000
IP : 0.5-4.0 ug for IP and 1:500-1:1000 for WB
IHC : 1:20-1:200

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
fibroblast growth factor 12

Calculated molecular weight:
181aa,20 kDa

Observed molecular weight:
20-25 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
FGF12

Synonyms
FGF 12, FGF12, FGF12B, FHF 1, FHF1, fibroblast growth factor 12, Myocyte activating factor
Background

FGF12 is a member of the fibroblast growth factor (FGF) family. FGF family members play important roles in embryogenesis, angiogenesis, and wound repair. FGF12 lacks the N-terminal signal sequence present in most of the FGF family members, but it contains clusters of basic residues that have been demonstrated to act as a nuclear localization signal. When transfected into mammalian cells, this protein accumulated in the nucleus, but was not secreted. FGF12 plays an intracellular role in the inhibition of radiation-induced apoptosis. FGF12 is expressed abundantly in developing and adult nervous systems; therefore, FGF12 was thought to be related to nervous system development and function.


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