GFPT1 Antibody 6 Publications

Rabbit Polyclonal| Catalog number: 14132-1-AP

Featured Product KD/KO validated

  • Print page
  • Download PDF

-_-

Freight/Packing

Con: 43 μg/150 μl

Choose size:

Please visit your regions distributor:


Species specificity:
human, mouse, rat, zebrafish

Positive WB detected in:
human skeletal muscle tissue, HepG2 cells

Positive IHC detected in:
human gliomas tissue,human hepatocirrhosis tissue

Positive IF detected in:
HepG2 cells

Recommended dilution:
WB : 1:500-1:1000
IHC : 1:50-1:500
IF : 1:20-1:200

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
glutamine-fructose-6-phosphate transaminase 1

Calculated molecular weight:
681aa,77 kDa

Observed molecular weight:
77 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
GFPT1

Synonyms
GFA, GFAT, GFAT 1, GFAT1, GFAT1m, GFPT, GFPT1
Background

GFPT1 (glutamine-fructose-6-phosphate transaminase 1) catalyzes the transfer of an amino group from glutamine onto fructose-6-phosphate, yielding glucosamine-6-phosphate (GlcN-6-P) and glutamate. GFPT1 is the key enzyme of the hexosamine pathway and is required for critical events in neuromuscular transmission. Mutations of GFPT1 cause congenital myasthenic syndromes (CMS). (21310273, 25765662)


Back
to top