RACK1 Antibody 1 Publications

Rabbit Polyclonal| Catalog number: 10076-1-AP

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Freight/Packing

Con: 20 μg/150 μl

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Species specificity:
human, mouse

Positive IHC detected in:
human lung cancer tissue

Positive IF detected in:
HeLa cells

Recommended dilution:
IHC : 1:50-1:500
IF : 1:50-1:500

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.1% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
guanine nucleotide binding protein (G protein), beta polypeptide 2-like 1

Calculated molecular weight:
36 kDa

Observed molecular weight:

GenBank accession number:

Gene ID (NCBI):

Gene symbol
GNB2L1

Synonyms
GNB2L1, H12.3, HLC 7, PIG21, RACK1
Background

Members of the protein kinase C (PKC) family play a key regulatory role in a variety of cellular functions, including cell growth and differentiation, gene expression, hormone secretion and membrane function. RACK1 (receptor for activated protein kinase C 1), encoded by GNB2L1 gene, is a 317 amino acid guanine nucleotide-binding protein subunit beta-2-like 1 protein which is involved in the recruitment, assembly and/or regulation of a variety of signaling molecules, it contains 7 WD-repeats and is implicated in various protein interaction activities. RACK1 is a component of the 40S ribosomal subunit involved in translational repression. Recent finding suggests that RACK1 may be a new promising diagnosis biomarker and therapeutic target for non-small-cell lung cancer (NSCLC).


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