GSK3B Antibody 1 Publications

Rabbit Polyclonal| Catalog number: 51065-1-AP

  • Print page
  • Download PDF

-_-

Freight/Packing

Con: 50 μg/150 μl

Choose size:

Please visit your regions distributor:


Species specificity:
human, mouse

Positive WB detected in:
HeLa cells, HEK-293 cells, HeLa cells

Positive IP detected in:
HeLa cells

Positive IHC detected in:
human prostate cancer tissue

Positive IF detected in:
NIH/3T3 cells, HeLa cells

Recommended dilution:
WB : 1:500-1:2000
IP : 0.5-4.0 ug for IP and 1:500-1:1000 for WB
IHC : 1:20-1:200
IF : 1:10-1:100

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Immunogen:
Peptide

Full name:
glycogen synthase kinase 3 beta

Calculated molecular weight:
433aa,48 kDa

Observed molecular weight:
46-52kd

GenBank accession number:

Gene ID (NCBI):

Gene symbol
GSK3B

Synonyms
GSK 3 beta, GSK3 beta, GSK3A B, GSK3B, GSK-3B, GSK3B 216P, gsk3beta
Background

Glycogen synthase kinase-3 (GSK3) is a proline-directed serine-threonine kinase that was initially identified as a phosphorylating and inactivating glycogen synthase .GSK3B is involved in energy metabolism, neuronal cell development, and body pattern formation.In skeletal muscle, it contributes to insulin regulation of glycogen synthesis by phosphorylating and inhibiting GYS1 activity and hence glycogen synthesis. Researches showed that the crystal structure of human GSK3B, expressed in insect cells, at 2.8-angstrom resolution .This antibody recognize the C-terminal of GSK3B.


Back
to top