GSNOR,ADH5 Antibody 0 Publications

Mouse Monoclonal| Catalog number: 66193-1-Ig |CloneNo.: 5E6E2

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Freight/Packing

Con: 114 μg/150 μl

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Species specificity:
human

Positive WB detected in:
fetal human brain tissue, human testis tissue

Positive IHC detected in:
human pancreas cancer tissue, human pancreas cancer tissue, human testis tissue

Positive IF detected in:
HepG2 cells

Recommended dilution:
WB : 1:1000-1:8000
IHC : 1:20-1:200
IF : 1:20-1:200

Product Information


Source:
Mouse

Purification method:
Protein G purification

Isotype:
IgG1

Storage:
PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
alcohol dehydrogenase 5 (class III), chi polypeptide

Calculated molecular weight:
374aa,40 kDa

Observed molecular weight:
40 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
ADH5

Synonyms
ADH 3, ADH5, ADHX, Alcohol dehydrogenase 5, Alcohol dehydrogenase class 3, FALDH, FDH, GSH FDH, GSNOR, GSNOR,ADH5
Background

ADH5, also named as ADHX, FDH FALDH GSH-FDH ADH3 and GSNOR, belongs to the zinc-containing alcohol dehydrogenase family and Class-III subfamily. It is remarkably ineffective in oxidizing ethanol, but it readily catalyzes the oxidation of long-chain primary alcohols and the oxidation of S-(hydroxymethyl) glutathione. ADH5 mediates multiple cardiovascular functions. It plays in regulating heterocellular communication in the artery wall. (PMID:21071693). ADH5 immunostaining is distributed in both the nucleus and cytoplasm of the retinal ganglion cells(PMID:22117533).


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