IFN Alpha Polyclonal antibody

IFN Alpha Polyclonal Antibody for WB, ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

WB, IHC, IF, ELISA

Conjugate

Unconjugated

Cat no : 18013-1-AP

Synonyms

IFL, IFN, IFN ALPHA, IFN alpha 1/13, IFNA@, IFNA1, IFNA13, Interferon alpha 1/13, Interferon alpha D, interferon, alpha 1, Interferon-α1, LeIF D



Tested Applications

Positive WB detected inRecombinant protein

Recommended dilution

ApplicationDilution
Western Blot (WB)WB : 1:1000-1:6000
Sample-dependent, check data in validation data gallery

Product Information

The immunogen of 18013-1-AP is IFN Alpha Fusion Protein expressed in E. coli.

Tested Reactivity human
Cited Reactivity human
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen IFN Alpha fusion protein Ag12533
Full Name IFNA1
Calculated molecular weight 189 aa, 22 kDa
GenBank accession numberBC074928
Gene symbol IFNA1
Gene ID (NCBI) 3439
Conjugate Unconjugated
Form Liquid
Purification Method Antigen affinity purification
Storage Buffer PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

Background Information

IFNA1 (IFN-alpha) is a member of the Type I IFN (1) family best known for their antiviral activity. It is a key cytokine regulating the activity of B cells, T-helper cells (Th cells), cDCs and natural killer cells (NK cells). IFN-alpha induces B cell maturation into plasma cells and immunoglobulin production. IFN-alpha plays an important role in the pathogenesis of systemic lupus erythematosus (SLE). IFN-alpha was the first cytokine to show clinical benefit in the treatment of certain types of cancer, including melanoma, chronic myelogenous leukemia, and renal cancer.

Protocols

Product Specific Protocols
WB protocol for IFN Alpha antibody 18013-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols

Publications

SpeciesApplicationTitle
humanIHC

Cancer Med

The preoperative neutrophil-to-lymphocyte ratio is not a marker of prostate cancer characteristics but is an independent predictor of biochemical recurrence in patients receiving radical prostatectomy.

Authors - Zhi Cao
humanWB

BMC Mol Cell Biol

Minicircle DNA vector expressing interferon-lambda-3 inhibits hepatitis B virus replication and expression in hepatocyte-derived cell line.

Authors - Xiaoyan Guo
humanIHC,IF

Clin Oral Investig

Hypermethylation of IFN-γ in oral cancer tissues.

Authors - Songbo Tian
humanWB

Dig Liver Dis

Innate and adaptive immunity in self-reported nonceliac gluten sensitivity versus celiac disease.

Authors - Antonio Di Sabatino