|Positive WB detected in||Recombinant protein|
|Western Blot (WB)||WB : 1:1000-1:6000|
|Sample-dependent, check data in validation data gallery|
The immunogen of 18013-1-AP is IFN Alpha Fusion Protein expressed in E. coli.
|Host / Isotype||Rabbit / IgG|
|Immunogen||IFN Alpha fusion protein Ag12533|
|Calculated molecular weight||189 aa, 22 kDa|
|GenBank accession number||BC074928|
|Gene ID (NCBI)||3439|
|Purification Method||Antigen affinity purification|
|Storage Buffer||PBS with 0.1% sodium azide and 50% glycerol pH 7.3.|
|Storage Conditions||Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.|
IFNA1 (IFN-alpha) is a member of the Type I IFN (1) family best known for their antiviral activity. It is a key cytokine regulating the activity of B cells, T-helper cells (Th cells), cDCs and natural killer cells (NK cells). IFN-alpha induces B cell maturation into plasma cells and immunoglobulin production. IFN-alpha plays an important role in the pathogenesis of systemic lupus erythematosus (SLE). IFN-alpha was the first cytokine to show clinical benefit in the treatment of certain types of cancer, including melanoma, chronic myelogenous leukemia, and renal cancer.
The preoperative neutrophil-to-lymphocyte ratio is not a marker of prostate cancer characteristics but is an independent predictor of biochemical recurrence in patients receiving radical prostatectomy.
BMC Mol Cell Biol
Minicircle DNA vector expressing interferon-lambda-3 inhibits hepatitis B virus replication and expression in hepatocyte-derived cell line.
Clin Oral Investig
Hypermethylation of IFN-γ in oral cancer tissues.
Dig Liver Dis
Innate and adaptive immunity in self-reported nonceliac gluten sensitivity versus celiac disease.