Integrin alpha-3 Antibody 1 Publications

Mouse Monoclonal| Catalog number: 66070-1-Ig |CloneNo.: 3F9G4

Featured Product KD/KO validated

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Freight/Packing

Con: 134 μg/150 μl

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Species specificity:
human, pig, mouse

Positive WB detected in:
PC-3 cells, A431 cells, HepG2 cells, A549 cells, mouse brain tissue

Positive FC detected in:
A549 cells

Recommended dilution:
WB : 1:500-1:2000

Product Information


Source:
Mouse

Purification method:
Protein A purification

Isotype:
IgG2a

Storage:
PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)

Calculated molecular weight:
1066aa,119 kDa

Observed molecular weight:
120 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
ITGA3

Synonyms
CD49C, FLJ34631, FLJ34704, FRP 2, Galactoprotein B3, GAP B3, GAPB3, Integrin alpha 3, ITGA3, MSK18, VCA 2, VL3A, VLA 3 subunit alpha, VLA3a
Background

ITGA3, also named as MSK18, CD49c, GAPB3 and FRP-2, belongs to the integrin alpha chain family. It is a receptor for fibronectin, laminin, collagen, epiligrin, thrombospondin and CSPG4. ITGA3 may mediate with LGALS3 the stimulation by CSPG4 of endothelial cells migration. ITGA3 is highly concentrated in epithelial cells where it strongly adheres to Laminin-5 and Laminin-5 induced rapid adhesion can be blocked by antibodies against the alpha-3 integrin subunit. It can be cleaved into heavy chain(840aa) and light chain(176aa). This antibody can recognize the heavy chain.


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