ITGA6X1A Antibody 0 Publications

Rabbit Polyclonal| Catalog number: 20231-1-AP

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Freight/Packing

Con: 26 μg/150 μl

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Species specificity:
human, mouse

Positive WB detected in:
mouse spleen tissue, mouse colon tissue

Recommended dilution:
WB : 1:200-1:1000

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Immunogen:
Peptide

Full name:
integrin, alpha 6

Calculated molecular weight:
127 kDa

Observed molecular weight:
100 kDa, 150 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
ITGA6

Synonyms
CD49f, DKFZp686J01244, FLJ18737, Integrin alpha 6, integrin, alpha 6, ITGA6, ITGA6B, VLA 6
Background

ITGA6, also named as CD49f and VLA-6, belongs to the integrin alpha chain family. It is a receptor for laminin on platelets. ITGA6 is a receptor for laminin in epithelial cells and it plays a critical structural role in the hemidesmosome. Defects in ITGA6 are a cause of epidermolysis bullosa letalis with pyloric atresia (EB-PA) which also known as junctional epidermolysis bullosa with pyloric atresia (PA-JEB) or aplasia cutis congenita with gastrointestinal atresia. The antibody is specific to isoform Alpha-6X1A, isoform Alpha-6X2A, isoform Alpha-6X1X2A isoform7 and isoform9 of ITGA6.


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