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KCNN4 Antibody

KCNN4 Polyclonal Antibody for IF, WB, ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

WB, IHC, IF, ELISA

Conjugate

Unconjugated

Cat no : 23271-1-AP

Synonyms

KCa3.1, KCNN4, SK4



Tested Applications

Positive WB detected inHEK-293 cells, HEK-293
Positive IF detected inHEK-293 cells

Recommended dilution

ApplicationDilution
Western Blot (WB)WB : 1:500-1:2000
Immunofluorescence (IF)IF : 1:50-1:500
Sample-dependent, check data in validation data gallery

Published Applications

IHCSee 1 publications below

Product Information

The 23271-1-AP immunogen is Fusion Protein KCNN4 protein expressed in E. coli.

Tested Reactivity human
Cited Reactivity human
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen KCNN4 fusion protein Ag19774
Full Name potassium intermediate/small conductance calcium-activated channel, subfamily N, member 4
Calculated molecular weight 427aa,48 kDa
Observed molecular weight 48 kDa
GenBank accession number BC015337
Gene symbol KCNN4
Gene ID (NCBI) 3783
Conjugate Unconjugated
Form Liquid
Purification Method Antigen Affinity purified
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

Background Information

The intermediate conductance calcium-activated potassium channel KCNN4, also known as KCa3.1, IK1, or SK4, is a member of the potassium channel KCNN family. KCNN4 is expressed in T cells, mast cells, macrophages, erythrocytes, vascular smooth muscle cells, airway smooth muscle cells, intestinal and airway epithelial cells (PMID: 19681865; 21493782). Functionally, KCNN4 plays a key role in calcium-dependent cell functions, such as proliferation, activation, and migration, in a broad range of cell types (PMID: 21493782).

Protocols

Product Specific Protocols
WB protocol for KCNN4 antibody 23271-1-APDownload protocol
IF protocol for KCNN4 antibody 23271-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols

Publications

SpeciesApplicationTitle
humanIHC

Biochem Biophys Res Commun

Integrated expression profiling of potassium channels identifys KCNN4 as a prognostic biomarker of pancreatic cancer.

Authors - Shuheng Jiang