KCNN4 Antibody 0 Publications

Rabbit Polyclonal| Catalog number: 23271-1-AP

Featured Product KD/KO validated

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Con: 57 μg/150 μl

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Species specificity:
human

Positive WB detected in:
HEK-293 cells, HEK-293

Positive IF detected in:
HEK-293 cells

Recommended dilution:
WB : 1:500-1:2000
IF : 1:50-1:500

Product Information


Source:
Rabbit

Purification method:
Antigen Affinity purified

Isotype:
IgG

Storage:
PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
potassium intermediate/small conductance calcium-activated channel, subfamily N, member 4

Calculated molecular weight:
427aa,48 kDa

Observed molecular weight:
48 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
KCNN4

Synonyms
KCa3.1, KCNN4, SK4
Background

The intermediate conductance calcium-activated potassium channel KCNN4, also known as KCa3.1, IK1, or SK4, is a member of the potassium channel KCNN family. KCNN4 is expressed in T cells, mast cells, macrophages, erythrocytes, vascular smooth muscle cells, airway smooth muscle cells, intestinal and airway epithelial cells (PMID: 19681865; 21493782). Functionally, KCNN4 plays a key role in calcium-dependent cell functions, such as proliferation, activation, and migration, in a broad range of cell types (PMID: 21493782).


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