MYOM3 Antibody 1 Publications

Rabbit Polyclonal| Catalog number: 17692-1-AP

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Con: 40 μg/150 μl

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Species specificity:
human, mouse

Positive WB detected in:
mouse skeletal muscle tissue

Positive IP detected in:
mouse skeletal muscle tissue

Positive IHC detected in:
human skeletal muscle tissue

Recommended dilution:
WB : 1:500-1:2000
IP : 0.5-4.0 ug for IP and 1:500-1:1000 for WB
IHC : 1:20-1:400

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
myomesin family, member 3

Calculated molecular weight:
162 kDa,136 kDa

Observed molecular weight:
162 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
MYOM3

Synonyms
FLJ35961, MYOM3, Myomesin 3, Myomesin family member 3, myomesin family, member 3, RP11 293P20.1
Background

MYOM3 (myomesin 3) is a structural component of the M-band in striated muscle and is involved in sarcomere stability and resistance during intense or sustained stretching. MYOM3 can be detected mainly in intermediate speed fibers of skeletal muscle. Recently high level of MYOM3 fragments were detected in sera from patients with muscular dystrophy, including Duchenne muscular dystrophy (DMD). MYOM3 fragments may be used as serum biomarker for DMD and other neuromuscular disorders. This antibody recognizes the intact MYOM3 protein (160-160 kDa) as well as MYOM3 fragments (100 kDa and 130 kDa). (26060189)


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