PDE4D Antibody 4 Publications

Rabbit Polyclonal| Catalog number: 12918-1-AP

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Con: 21 μg/150 μl

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Species specificity:
human, mouse, rat

Positive WB detected in:
mouse brain tissue, mouse pancreas tissue

Positive IHC detected in:
mouse colon tissue

Recommended dilution:
WB : 1:500-1:3000
IHC : 1:50-1:500

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
phosphodiesterase 4D, cAMP-specific (phosphodiesterase E3 dunce homolog, Drosophila)

Calculated molecular weight:
809aa,91 kDa

Observed molecular weight:
91 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
PDE4D

Synonyms
DPDE3, HSPDE4D, PDE43, PDE4D, PDE4DN2, STRK1
Background

PDE4D(cAMP-specific 3',5'-cyclic phosphodiesterase 4D) is also named as DPDE3, PDE43 and belongs to the cyclic nucleotide phosphodiesterase family and PDE4 subfamily. PDE4D subtype may be of particular importance as an antidepressant target in that it is regulated by repeated treatment with both norepinephrine and serotonin reuptake inhibitors as well as by the PDE4 inhibitor rolipram(PMID:16730340). It has at least 9 isoforms and all 9 PDE4D isoforms are expressed in healthy adult human hippocampus and in hippocampus from a patient with advanced Alzheimer disease(PMID:17353396).


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