PI3K p110(alpha) Antibody 4 Publications

Rabbit Polyclonal| Catalog number: 20583-1-AP

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Con: 29 μg/150 μl

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Tested Applications

Applications:
ELISA, IHC, WB
Application not tested? Please see our Guarantee




Species specificity:
human, mouse, rat

Recommended dilution:

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Immunogen:
Peptide

Full name:
phosphoinositide-3-kinase, catalytic, alpha polypeptide

Calculated molecular weight:
124 kDa

Observed molecular weight:
120-130 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
PIK3CA

Synonyms
p110 alpha, PI3 kinase subunit alpha, PI3K, PI3K alpha, PI3K p110(alpha), PI3-kinase p110 subunit alpha, PIK3CA, PtdIns 3 kinase subunit alpha
Background

PIK3CA belongs to the PI3/PI4-kinase family. It phosphorylates PtdIns, PtdIns4P and PtdIns(4,5)P2 with a preference for PtdIns(4,5)P2. Defects in PIK3CA are associated with colorectal cancer (CRC). Defects in PIK3CA are associated with breast cancer. Defects in PIK3CA are associated with ovarian cancer. Defects in PIK3CA may underlie hepatocellular carcinoma (HCC). Defects in PIK3CA are a cause of keratosis seborrheic (KERSEB). The antibody is specific to PIK3CA.


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