PURA Antibody 0 Publications

Rabbit Polyclonal| Catalog number: 17733-1-AP

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Freight/Packing

Con: 32 μg/150 μl

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Species specificity:
human, mouse, rat

Positive WB detected in:
HeLa cells, HepG2 cells, human liver tissue

Recommended dilution:
WB : 1:500-1:2000

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
purine-rich element binding protein A

Calculated molecular weight:
322aa,35 kDa

Observed molecular weight:
47 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
PURA

Synonyms
PUR ALPHA, PUR1, PURA, PURALPHA
Background

PURA, also named as Transcriptional activator protein Pur-alpha, is a 322 amino acid protein, which belongs to the PUR DNA-binding protein family and can form homodimer or heterodimer with PURB and heterotrimer with PURB and YBX1/Y-box protein 1. PURA is a probable transcription activator that specifically binds the purine-rich single strand of the PUR element located upstream of the MYC gene and may play a role in the initiation of DNA replication and in recombination. The calcualted molecular weight of PURA is 35 kDa, but modified PURA is 47 kDa. (PMID: 9716182)


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