TLR4 Antibody 2 Publications

Mouse Monoclonal| Catalog number: 66350-1-Ig |CloneNo.: 3G9A4

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Con: 116 μg/150 μl

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Species specificity:
human, mouse, rat

Positive WB detected in:
RAW 264.7 cells

Positive IHC detected in:
human tonsillitis tissue

Recommended dilution:
WB : 1:1000-1:8000
IHC : 1:50-1:500

Product Information


Source:
Mouse

Purification method:
Protein A purification

Isotype:
IgG2b

Storage:
PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
toll-like receptor 4

Calculated molecular weight:
839aa,96 kDa

Observed molecular weight:
100 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
TLR4

Synonyms
ARMD10, CD284, hToll, TLR4, TOLL, toll like receptor 4
Background

TLR4, also named as CD284, belongs to the Toll-like receptor family. TLR4 cooperates with LY96 and CD14 to mediates the innate immune response to bacterial lipopolysaccharide (LPS). TLR4 acts via MYD88, TIRAP and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Three alternatively spliced transcript variants that encode different protein isoforms have been described.


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