|Positive WB detected in||human brain tissue, mouse large intestine tissue, mouse skeletal muscle tissue, HeLa cells, mouse liver tissue, MCF-7 cells, L02 cells, mouse spleen tissue, mouse brain tissue, human skeletal muscle tissue, HepG2 cells, human heart tissue, mouse kidney tissue|
|Positive IP detected in||HeLa cells|
|Positive IHC detected in||human heart tissue, human liver tissue|
Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0
|Positive IF detected in||HepG2 cells|
|Western Blot (WB)||WB : 1:1000-1:4000|
|Immunoprecipitation (IP)||IP : 0.5-4.0 ug for IP and 1:500-1:1000 for WB|
|Immunohistochemistry (IHC)||IHC : 1:20-1:200|
|Immunofluorescence (IF)||IF : 1:10-1:100|
|Sample-dependent, check data in validation data gallery|
The immunogen of 21705-1-AP is UQCRC1 Fusion Protein expressed in E. coli.
|Tested Reactivity||human, mouse, rat|
|Cited Reactivity||human, mouse|
|Host / Isotype||Rabbit / IgG|
|Immunogen||UQCRC1 fusion protein Ag16322|
|Full Name||ubiquinol-cytochrome c reductase core protein I|
|Calculated molecular weight||480 aa, 53 kDa|
|Observed molecular weight||45 kDa|
|GenBank accession number||BC009586|
|Gene ID (NCBI)||7384|
|Purification Method||Antigen affinity purification|
|Storage Buffer||PBS with 0.02% sodium azide and 50% glycerol pH 7.3.|
|Storage Conditions||Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.|
UQCRC1(Cytochrome b-c1 complex subunit 1, mitochondrial), also named as QCR1 and UQCR1, is a ubunit of the cytochrome bc1 complex (complex III) of the mitochondrial respiratory chain, may mediate the formation of the complex between cytochromes c and c1. The gene encodes a 53 kDa protein with a 34 amino acids transit peptide. It is associated with apoptosis or inhibition of cancer cell growth.
|Product Specific Protocols|
|WB protocol for UQCRC1 antibody 21705-1-AP||Download protocol|
|IHC protocol for UQCRC1 antibody 21705-1-AP||Download protocol|
|IF protocol for UQCRC1 antibody 21705-1-AP||Download protocol|
|IP protocol for UQCRC1 antibody 21705-1-AP||Download protocol|
|Click here to view our Standard Protocols|
The SIAH2-NRF1 axis spatially regulates tumor microenvironment remodeling for tumor progression.
Mol Cell Biol
Iron supply via NCOA4-mediated ferritin degradation maintains mitochondrial functions.
CYC1 Predicts Poor Prognosis in Patients with Breast Cancer.
DNA Cell Biol
Inhibition of the ox-LDL-Induced Pyroptosis by FGF21 of Human Umbilical Vein Endothelial Cells Through the TET2-UQCRC1-ROS Pathway.
Acta Pharmacol Sin
Benzoylaconine induces mitochondrial biogenesis in mice via activating AMPK signaling cascade.
Tetramethylpyrazine ameliorates high glucose-induced endothelial dysfunction by increasing mitochondrial biogenesis.