Recombinant Mouse CCL6 protein (rFc Tag)
Species
Mouse
Purity
>90 %, SDS-PAGE
Tag
C-rFc
Activity
not tested
Cat no : Eg2957
Validation Data Gallery
Product Information
| Purity | >90 %, SDS-PAGE |
| Endotoxin | <0.1 EU/μg protein, LAL method |
| Activity |
Not tested |
| Expression | HEK293-derived Mouse CCL6 protein Gly22-Ala116 (Accession# P27784) with a rabbit IgG Fc tag at the C-terminus. |
| GeneID | 20305 |
| Accession | P27784 |
| PredictedSize | 36.8 kDa |
| SDS-PAGE | 37-43 kDa, reducing (R) conditions |
| Formulation | Lyophilized from 0.22 μm filtered solution in PBS, pH 7.4. Normally 5% trehalose and 5% mannitol are added as protectants before lyophilization. |
| Reconstitution | Briefly centrifuge the tube before opening. Reconstitute at 0.1-0.5 mg/mL in sterile water. |
| Storage Conditions |
It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
|
| Shipping | The product is shipped at ambient temperature. Upon receipt, store it immediately at the recommended temperature. |
Background
CCL6 is a selective CCR1 ligand, and although it does not exist in humans, it is considered to have the human orthologs CCL15 and CCL23. Further investigation is needed to determine the role of CCL6 after PNS and CNS injury, and it would also be worthwhile to investigate the role of CCL15 and CCL23 in patients.
References:
1. Li F., et al. Sci. Adv. 2021;7:5943–5969. 2. Kanno M., et al. J. Neuroimmunol. 2005;167:72–80. 3. Du X., et al. Signal Transduct. Target. Ther. 2021 61. 2021;6:91.