Recombinant Human PSG1 protein (rFc Tag)
Species
Human
Purity
>90 %, SDS-PAGE
Tag
rFc Tag
Activity
not tested
Cat no : Eg3704
Validation Data Gallery
Product Information
| Purity | >90 %, SDS-PAGE |
| Endotoxin | <0.1 EU/μg protein, LAL method |
| Activity |
Not tested |
| Expression | HEK293-derived Human PSG1 protein Gln35-Pro419 (Accession# P11464-1) with a rabbit IgG Fc tag at the C-terminus. |
| GeneID | 5669 |
| Accession | P11464-1 |
| PredictedSize | 69.8 kDa |
| SDS-PAGE | 80-90 kDa, reducing (R) conditions |
| Formulation | Lyophilized from 0.22 μm filtered solution in PBS, pH 7.4. Normally 5% trehalose and 5% mannitol are added as protectants before lyophilization. |
| Reconstitution | Briefly centrifuge the tube before opening. Reconstitute at 0.1-0.5 mg/mL in sterile water. |
| Storage Conditions |
It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
|
| Shipping | The product is shipped at ambient temperature. Upon receipt, store it immediately at the recommended temperature. |
Background
Pregnancy-specific β-glycoprotein 1 (PSG1) is synthesized by the human placenta and is secreted into the maternal circulation in increasing concentration from the time of trophoblast differentiation until term. PSG1 is the most abundantly expressed of the 11 different PSG genes, which reach a median concentration of 168μg/ml at week 36 of pregnancy, when a plateau is reached.
References:
1. Zhou GQ, et al. Placenta. 1997;18(7):491–501. 2. Pluta M, et al. Arch Gynecol. 1979;227(4):327–336.