ACE2 Antibody 0 Publications

Rabbit Polyclonal| Catalog number: 21115-1-AP

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Freight/Packing

Con: 64 μg/150 μl

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Species specificity:
human, mouse, rat

Positive WB detected in:
mouse kidney tissue, human skeletal muscle tissue

Positive IP detected in:
mouse kidney tissue

Recommended dilution:
WB : 1:1000-1:4000
IP : 0.5-4.0 ug for IP and 1:500-1:2000 for WB

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
angiotensin I converting enzyme (peptidyl-dipeptidase A) 2

Calculated molecular weight:
805aa,92 kDa

Observed molecular weight:
90-110 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
ACE2

Synonyms
ACE related carboxypeptidase, ACE2, ACEH, Angiotensin converting enzyme 2, DKFZp434A014, Metalloprotease MPROT15
Background

ACE2 contains a potential 17-amino acid N-terminal signal peptide and a putative 22-amino acid C-terminal membrane anchor. It is the only known mammalian homologue of the zinc-metallopeptidase angiotensin-converting enzyme (ACE), a critical regulator of the reninangiotensin system.ACE2 has a more restricted tissue distribution than ACE, being found predominantly in the heart, kidneys, and testes although low levels have been detected in a variety of tissues(PMID:15983030). It can be N-Deglycosylation(PMID:16166094).It has 2 isoforms produced by alternative splicing.This antibody is specific to ACE2.


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