ADARB1 Antibody 1 Publications

Rabbit Polyclonal| Catalog number: 22248-1-AP

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Freight/Packing

Con: 35 μg/150 μl

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Species specificity:
human, rat, mouse

Positive WB detected in:
rat brain tissue, A431 cells

Positive IP detected in:
A431 cells

Recommended dilution:
WB : 1:500-1:2000
IP : 0.5-4.0 ug for IP and 1:500-1:2000 for WB

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
adenosine deaminase, RNA-specific, B1 (RED1 homolog rat)

Calculated molecular weight:
741aa,81 kDa

Observed molecular weight:
70 kDa,80 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
ADARB1

Synonyms
ADAR2, ADAR2a, ADAR2a L1, ADAR2a L2, ADAR2a L3, ADAR2b, ADAR2c, ADAR2d, ADAR2g, ADARB1, DRABA2, DRADA2, dsRNA adenosine deaminase, RED1, RNA editing deaminase 1, RNA editing enzyme 1
Background

ADARB1(Double-stranded RNA-specific editase 1) is also named as ADAR2, DRADA2, RED1 and belongs to the ADAR family. It catalyses the deamination of adenosine to inosine at the GluR2 Q/R site in the pre-mRNA encoding the critical subunit of AMPA receptors. This protein has 5 isoforms with the molecular weight from 77 kDa to 81 kDa and 7 kDa, but it can be detected a very strong band at 50 kDa in addition to a predicted band at 75 kDa as the result of western blot, while ADARB1 has several alternative splice variants(PMID:23103828).


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