Product Information
85769-4-PBS targets AKT3 in WB, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.
Tested Reactivity | human, mouse, rat |
Host / Isotype | Rabbit / IgG |
Class | Recombinant |
Type | Antibody |
Immunogen | AKT3 fusion protein Ag16298 Predict reactive species |
Full Name | v-akt murine thymoma viral oncogene homolog 3 (protein kinase B, gamma) |
Calculated Molecular Weight | 465 aa, 54 kDa |
Observed Molecular Weight | 60 kDa |
GenBank Accession Number | BC121154 |
Gene Symbol | AKT3 |
Gene ID (NCBI) | 10000 |
Conjugate | Unconjugated |
Form | Liquid |
Purification Method | Protein A purification |
UNIPROT ID | Q9Y243 |
Storage Buffer | PBS only, pH 7.3. |
Storage Conditions | Store at -80°C. |
Background Information
AKT3, also named as PKBG, is one of 3 closely related serine/threonine-protein kinases (AKT1, AKT2 and AKT3) called the AKT kinase, and which regulate many processes including metabolism, proliferation, cell survival, growth and angiogenesis. AKT3 is a key modulator of several tumors like melanoma, glioma and ovarian cancer. Active AKT3 increases progressively during melanoma tumor progression with highest levels present in advanced-stage metastatic melanomas.