ALMS1 Polyclonal antibody

ALMS1 Polyclonal Antibody for IF, FC, ELISA

Host / Isotype

Rabbit / IgG







Cat no : 27231-1-AP


ALMS1, ALSS, Alstrom syndrome 1, Alstrom syndrome protein 1, KIAA0328

Tested Applications

Positive IF detected inHeLa cells
Positive FC detected inHeLa cells

Recommended dilution

Immunofluorescence (IF)IF : 1:50-1:500
Flow Cytometry (FC)FC : 1:10-1:100
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

Product Information

27231-1-AP targets ALMS1 in IF, FC, ELISA applications and shows reactivity with human samples.

Tested Reactivity human
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen ALMS1 fusion protein Ag26100
Full Name Alstrom syndrome 1
Calculated Molecular Weight 461 kDa
GenBank Accession NumberNM_015120
Gene Symbol ALMS1
Gene ID (NCBI) 7840
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. 20ul sizes contain 0.1% BSA.

Background Information

ALMS1 (Alstrom syndrome protein 1) is also KIAA0328. ALMS1 encodes a ~ 0.5 megadalton protein that localises to the base of centrioles. Some studies have suggested a role for this protein in maintaining centriole-nucleated sensory organelles termed primary cilia, and AS is now considered to belong to the growing class of human genetic disorders linked to ciliary dysfunction (ciliopathies). The ALMS1 protein is a component of the centrosome (PMID:30421101). ALMS1 is involved in PCM1-dependent intracellular transport. ALMS1 is required, directly or indirectly, for the localization of NCAPD2 to the proximal ends of centrioles. It is required for proper formation and/or maintenance of primary cilia (PC), microtubule-based structures that protrude from the surface of epithelial cells.


Product Specific Protocols
IF protocol for ALMS1 antibody 27231-1-APDownload protocol
FC protocol for ALMS1 antibody 27231-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols