AP3M1 Antibody 1 Publications

Rabbit Polyclonal| Catalog number: 12114-1-AP

Featured Product KD/KO validated

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Freight/Packing

Con: 26 μg/150 μl

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Species specificity:
human, mouse, rat

Positive WB detected in:
NIH/3T3 cells

Positive IP detected in:
NIH/3T3 cells

Recommended dilution:
WB : 1:500-1:2000
IP : 0.5-4.0 ug for IP and 1:200-1:1000 for WB

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.1% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
adaptor-related protein complex 3, mu 1 subunit

Calculated molecular weight:
418aa,47 kDa

Observed molecular weight:
47 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
AP3M1

Synonyms
AP 3 complex subunit mu 1, AP3M1, Mu adaptin 3A, Mu3A adaptin
Background

Adaptor protein (AP) complexes are cytosolic heterotetramers that mediate the sorting of membrane proteins in the secretory and endocytic pathways. AP3M1 is a subunit of the AP-3 complex which is composed of two large adaptins (AP3D1 and AP3B1 or AP3B2), a medium adaptin (AP3M1 or AP3M2) and a small adaptin (APS1 or AP3S2). AP-3 complex is associated with the Golgi region as well as more peripheral structures. It facilitates the budding of vesicles from the Golgi membrane and may be directly involved in trafficking to lysosomes.


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