Apelin Polyclonal antibody

Apelin Polyclonal Antibody for IHC, ELISA

Host / Isotype

Rabbit / IgG


human, mouse, rat





Cat no : 11497-1-AP


APEL, apelin, APJ endogenous ligand, APLN, XNPEP2

Tested Applications

Positive IHC detected inhuman colon cancer tissue, mouse heart tissue
Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0

Recommended dilution

Immunohistochemistry (IHC)IHC : 1:50-1:500
Sample-dependent, check data in validation data gallery

Product Information

11497-1-AP targets Apelin in IHC, ELISA applications and shows reactivity with human, mouse, rat samples.

Tested Reactivity human, mouse, rat
Cited Reactivitymouse, rat
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen Apelin fusion protein Ag2047
Full Name apelin
Calculated molecular weight 77 aa, 9 kDa
GenBank accession numberBC021104
Gene symbol APLN
Gene ID (NCBI) 8862
Conjugate Unconjugated
Form Liquid
Purification Method Antigen affinity purification
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

Background Information

Apelin, isolated from bovine stomach tissue extractsis, is recognized as the endogenous ligand of the angiotensin-like-receptor 1 (APJ), and the human orphan G-protein-coupled receptor. Apelin is widely expressed in various organs such as the heart, lung, kidney, liver, adipose tissue, gastrointestinal tract, brain, adrenal glands, endothelium, and human plasma. Apelin has been found to be a potent stimulator of cardiac contractility and may function in the regulation of the cardiovascular system. Apelin is also known to be involved in the maintenance of INS sensitivity and play an important role in liver disease.


Product Specific Protocols
IHC protocol for Apelin antibody 11497-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols



Free Radic Biol Med

Apelin-13 induces mitophagy in bone marrow mesenchymal stem cells to suppress intracellular oxidative stress and ameliorate osteoporosis by activation of AMPK signaling pathway

Authors - Liang Chen


Maternal exercise intergenerationally drives muscle-based thermogenesis via activation of apelin-AMPK signaling.

Authors - Jun Seok Son

Front Pharmacol

Apelin-13 Suppresses Neuroinflammation Against Cognitive Deficit in a Streptozotocin-Induced Rat Model of Alzheimer's Disease Through Activation of BDNF-TrkB Signaling Pathway.

Authors - Huaiqing Luo


Apelin-13 Upregulates BDNF Against Chronic Stress-induced Depression-like Phenotypes by Ameliorating HPA Axis and Hippocampal Glucocorticoid Receptor Dysfunctions.

Authors - Ting-Ting Dai


The Hippocampus is a Critical Site Mediating Antidepressant-like Activity of Apelin-13 in Rats.

Authors - Zhi-Yong Xiao

Sci Adv

Maternal exercise via exerkine apelin enhances brown adipogenesis and prevents metabolic dysfunction in offspring mice.

Authors - Jun Seok Son