AXIN1 Monoclonal antibody

AXIN1 Monoclonal Antibody for WB, ELISA

Host / Isotype

Mouse / IgG1


Human, mouse, rat







Cat no : 68093-1-Ig


AXIN, axin 1, AXIN1, Axis inhibition protein 1, hAxin

Tested Applications

Positive WB detected inA431 cells, HSC-T6 cells, NIH/3T3 cells, MCF-7 cells, HeLa cells, HEK-293 cells, HepG2 cells, Jurkat cells, K-562 cells

Recommended dilution

Western Blot (WB)WB : 1:5000-1:50000
Sample-dependent, check data in validation data gallery

Product Information

68093-1-Ig targets AXIN1 in WB, ELISA applications and shows reactivity with Human, mouse, rat samples.

Tested Reactivity Human, mouse, rat
Host / Isotype Mouse / IgG1
Class Monoclonal
Type Antibody
Immunogen AXIN1 fusion protein Ag10079
Full Name axin 1
Calculated molecular weight826aa,92 kDa; 862aa,95 kDa
Observed molecular weight110-120 kDa
GenBank accession numberBC044648
Gene symbol AXIN1
Gene ID (NCBI) 8312
Conjugate Unconjugated
Form Liquid
Purification Method Protein G purification
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. 20ul sizes contain 0.1% BSA.

Background Information

Axis inhibition protein1 (AXIN1), also called AXIN, together with AXIN2 are multidomain scaffold proteins that negatively regulate Wnt signaling. AXIN1 is likely to function as a tumor suppressor. Under UV irradiation, AXIN1-HIPK2-TP53 complex forms. The complex also controls cell growth, apoptosis and development. Like AXIN2, AXIN1 undergoes poly(ADP-ribosy)lation by tankyrase TNKS and TNKS2 followed by unbiquitination by RNF146 which leads to its degradation and subsequent activation of Wnt signaling. Its deubiquitination by USP34 is important for nuclear accumulation during Wnt signaling. Proteintech's AXIN1 antibody 16541-1-AP is a rabbit polyclonal antibdy raised against the N-terminus of human AXIN1.


Product Specific Protocols
WB protocol for AXIN1 antibody 68093-1-IgDownload protocol
Standard Protocols
Click here to view our Standard Protocols