Amylin Polyclonal antibody
Amylin Polyclonal Antibody for IHC,ELISA
Host / Isotype
Rabbit / IgG
human, rat, mouse
Cat no : 22305-1-AP
Validation Data Gallery
|Positive IHC detected in
|human pancreas tissue, mouse pancreas tissue, rat pancreas tissue
Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0
|IHC : 1:20-1:200
|It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
|Sample-dependent, check data in validation data gallery
22305-1-AP targets Amylin in IHC,ELISA applications and shows reactivity with human, rat, mouse samples.
|human, rat, mouse
|Host / Isotype
|Rabbit / IgG
|islet amyloid polypeptide
|Calculated molecular weight
|GenBank accession number
|Gene ID (NCBI)
|Antigen Affinity purified
|PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
|Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. 20ul sizes contain 0.1% BSA.
IAPP, also known as Amylin, is commonly found in pancreatic islets of patients suffering diabetes mellitus type II, or harboring a tumor of the pancreas that is derived from beta cells and secretes INS. IAPP is co-secreted with INS by pancreatic β-cells and largely contributes to glycemic control. Studies suggest that this protein, like the related beta-amyloid (Abeta) associated with Alzheimer's disease, can induce apoptotic cell-death in particular cultured cells, an effect that may be relevant to the development of type II diabetes.