- Featured Product
- KD/KO Validated
BMP2 Polyclonal antibody
BMP2 Polyclonal Antibody for WB, ELISA
Host / Isotype
Rabbit / IgG
human and More (4)
WB, IHC, IF, ELISA
Cat no : 18933-1-AP
|Positive WB detected in||HeLa cells|
|Western Blot (WB)||WB : 1:500-1:1000|
|Sample-dependent, check data in validation data gallery|
|KD/KO||See 2 publications below|
|WB||See 46 publications below|
|IHC||See 12 publications below|
|IF||See 6 publications below|
The immunogen of 18933-1-AP is BMP2 Fusion Protein expressed in E. coli.
|Cited Reactivity||human, mouse, rat, hamster, sheep|
|Host / Isotype||Rabbit / IgG|
|Immunogen||BMP2 fusion protein Ag13501|
|Full Name||bone morphogenetic protein 2|
|Calculated molecular weight||396 aa, 44 kDa|
|GenBank accession number||BC069214|
|Gene ID (NCBI)||650|
|Purification Method||Antigen affinity purification|
|Storage Buffer||PBS with 0.02% sodium azide and 50% glycerol pH 7.3.|
|Storage Conditions||Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. 20ul sizes contain 0.1% BSA.|
Bone morphogenetic protein-2 (BMP-2) is a member of the transforming growth factor-beta (TGFB) superfamily. BMP2 is synthesized as a 60 kDa precursor that is processed in the secretory pathway to a small 18 kDa monomer; 2 monomers then associate to form the active 30 kDa homodimer, which binds to its receptor. There is also a 40-45 kDa form of BMP2, as an amino-terminal propeptide. BMP2 can induce bone formation and regeneration during early embryonic development. It is involved in the hedgehog pathway, TGF beta signaling pathway, and cytokine-cytokine receptor interaction.
|Product Specific Protocols|
|WB protocol for BMP2 antibody 18933-1-AP||Download protocol|
|Click here to view our Standard Protocols|
Guided bone regeneration is promoted by the molecular events in the membrane compartment.
A fucoidan from Nemacystus decipiens disrupts angiogenesis through targeting bone morphogenetic protein 4.
Arterioscler Thromb Vasc Biol
Overexpression of c1q/tumor necrosis factor-related protein-3 promotes phosphate-induced vascular smooth muscle cell calcification both in vivo and in vitro.
Antioxid Redox Signal
Role of Nox4 in high calcium-induced renal oxidative stress damage and crystal deposition.
Free Radic Biol Med
Metformin attenuates hyperlipidaemia-associated vascular calcification through anti-ferroptotic effects.
Postnatal eye size in mice is controlled by SREBP2-mediated transcriptional repression of Lrp2 and Bmp2.