• Featured Product
  • KD/KO Validated

BTG2 Polyclonal antibody

BTG2 Polyclonal Antibody for IF, FC, IHC, ELISA

Host / Isotype

Rabbit / IgG


human, mouse





Cat no : 22339-1-AP


BTG family member 2, BTG family, member 2, BTG2, PC3, Protein BTG2, TIS21

Tested Applications

Positive IHC detected inmouse small intestine tissue, human kidney tissue
Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0
Positive IF detected inNeuro-2a cells
Positive FC detected inSH-SY5Y cells, Neuro-2a cells

Recommended dilution

Immunohistochemistry (IHC)IHC : 1:50-1:500
Immunofluorescence (IF)IF : 1:200-1:800
Flow Cytometry (FC)FC : 0.40 ug per 10^6 cells in a 100 µl suspension
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

Product Information

22339-1-AP targets BTG2 in WB, IF, FC, IHC, ELISA applications and shows reactivity with human, mouse samples.

Tested Reactivity human, mouse
Cited Reactivityhuman, mouse
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen BTG2 fusion protein Ag17819
Full Name BTG family, member 2
Calculated Molecular Weight 158 aa, 17 kDa
GenBank Accession NumberBC105949
Gene Symbol BTG2
Gene ID (NCBI) 7832
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. 20ul sizes contain 0.1% BSA.

Background Information

Protein BTG2, the anti-proliferative human homolog of murine Pc3/Tis21, belongs to the BTG/Tob family. This family has structurally related proteins that appear to have anti-proliferative properties. It has been demonstrated that BTG2 is p53-inducible and is involved in cell cycle control and cellular response to DNA damage (PMID: 8944033). As a transcriptional co-regulator, BTG2 has been shown to interact with CAF1 and POP2, and works as a co-activator of ERa-mediated transcription via a CCR4-like complex (PMID: 18974182).


Product Specific Protocols
IHC protocol for BTG2 antibody 22339-1-APDownload protocol
IF protocol for BTG2 antibody 22339-1-APDownload protocol
FC protocol for BTG2 antibody 22339-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols



Front Oncol

Transcriptomic Analyses Reveal B-Cell Translocation Gene 2 as a Potential Therapeutic Target in Ovarian Cancer.

Authors - Jia Wang
  • KD Validated


MicroRNA-409-3p/BTG2 signaling axis improves impaired angiogenesis and wound healing in obese mice

Authors - Furkan Bestepe

ACS Chem Biol

Epitranscriptomic N6-Methyladenosine Modification Is Required for Direct Lineage Reprogramming into Neurons.

Authors - Hwan Choi

Front Mol Biosci

Development and Validation of a 7-Gene Inflammatory Signature Forecasts Prognosis and Diverse Immune Landscape in Lung Adenocarcinoma.

Authors - Aitao Nai

J Oncol

lncRNA SNHG5 Modulates Endometrial Cancer Progression via the miR-25-3p/BTG2 Axis.

Authors - Shi Li

Dig Dis Sci

BTG2 Is Down-Regulated and Inhibits Cancer Stem Cell-Like Features of Side Population Cells in Hepatocellular Carcinoma.

Authors - Chen-Song Huang


The reviews below have been submitted by verified Proteintech customers who received an incentive forproviding their feedback.


Tianyi (Verified Customer) (01-12-2024)

Antigen retrieval in TE buffer, incubated with AF488 at room temperature for 2 h.

  • Applications: Immunofluorescence
  • Primary Antibody Dilution: 1:100
  • Cell Tissue Type: Ovarian tissue