CA6 Monoclonal antibody

CA6 Monoclonal Antibody for WB, ELISA

Host / Isotype

Mouse / IgM

Reactivity

human

Applications

WB, ELISA

Conjugate

Unconjugated

CloneNo.

1C8C7

Cat no : 66909-1-Ig

Synonyms

EC:4.2.1.1, CA-VI, Carbonic anhydrase 6, Carbonate dehydratase VI, CA VI

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Validation Data Gallery

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  WB analysis of human saliva using 66909-1-Ig

  human saliva were subjected to SDS PAGE followed by western blot with 66909-1-Ig (CA6 antibody) at dilution of 1:2500 incubated at room temperature for 1.5 hours.

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Tested Applications

• Positive WB detected in: human saliva tissue

Recommended dilution

• Western Blot (WB): WB : 1:1000-1:5000

It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Sample-dependent, Check data in validation data gallery.

Product Information

66909-1-Ig targets CA6 in WB, ELISA applications and shows reactivity with human samples.

• Tested Reactivity: human
• Host / Isotype: Mouse / IgM
• Class: Monoclonal
• Type: Antibody
• Immunogen: CA6 fusion protein Ag24274
• Full Name: carbonic anhydrase VI
• Calculated Molecular Weight: 35 kDa
• Observed Molecular Weight: 38 kDa
• GenBank Accession Number: BC034350
• Gene Symbol: CA6
• Gene ID (NCBI): 765
• RRID: AB_2882236
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Antigen affinity purification
• Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
• Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20^oC storage. 20ul sizes contain 0.1% BSA.

Background Information

CA6 (Carbonic anhydrase VI ) is a member of CA family proteins that play a central role in pH regulation and electrolyte balance. CA6 is also known as gustin, is a zinc-containing secreted protein which catalyzes the hydration of carbon hydroxide in saliva. CA6 is specifically expressed in the salivary gland of a number of mammalian species (PMID:28423504). The amino acid sequences are highly conserved across the species. And it was reported that decreasing of CA6 protein was associated with loss of taste and pathological morphology of taste buds (PMID: 9784398).