CABC1 Polyclonal antibody

CABC1 Polyclonal Antibody for IF, WB, ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse, rat

Applications

WB, IF, ELISA

Conjugate

Unconjugated

Cat no : 15528-1-AP

Synonyms

ADCK3, ARCA2, CABC1, Chaperone ABC1 like, COQ8, COQ8A, SCAR9



Tested Applications

Positive WB detected inHeLa cells, human heart tissue, human skeletal muscle tissue, mouse heart tissue
Positive IF detected inHepG2 cells

Recommended dilution

ApplicationDilution
Western Blot (WB)WB : 1:1000-1:4000
Immunofluorescence (IF)IF : 1:50-1:500
Sample-dependent, check data in validation data gallery

Published Applications

WBSee 1 publications below

Product Information

15528-1-AP targets CABC1 in WB, IF, ELISA applications and shows reactivity with human, mouse, rat samples.

Tested Reactivity human, mouse, rat
Cited Reactivity mouse
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen CABC1 fusion protein Ag7612
Full Name chaperone, ABC1 activity of bc1 complex homolog (S. pombe)
Calculated molecular weight 72 kDa
Observed molecular weight 60 kDa
GenBank accession numberBC005171
Gene symbol CABC1
Gene ID (NCBI) 56997
Conjugate Unconjugated
Form Liquid
Purification Method Antigen affinity purification
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

Background Information

CABC1 (Chaperone, ABC1 activity of bc1 complex homolog) is induced by the tumor suppressor p53 and is similar to the yeast ABC1, which is involved in an electron-transferring membrane protein complex in the respiratory chain. The CABC1 product was located in mitochondria, and may play an important role in mediating p53-inducible apoptosis. Four isoforms of CABC1 exist due to alternative splicing events.

Protocols

Product Specific Protocols
WB protocol for CABC1 antibody 15528-1-APDownload protocol
IF protocol for CABC1 antibody 15528-1-APDownload protocol
IP protocol for CABC1 antibody 15528-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols

Publications

SpeciesApplicationTitle
mouseWB

EMBO Mol Med

β-RA reduces DMQ/CoQ ratio and rescues the encephalopathic phenotype in Coq9 R239X mice.

Authors - Agustín Hidalgo-Gutiérrez