CoraLite® Plus 488 Anti-Mouse CD16/32 (93)
CD16/32 Monoclonal Antibody for FC, IF
Host / Isotype
Rat / IgG2a, lambda
CoraLite® Plus 488 Fluorescent Dye
Cat no : CL488-65057
|Positive IF detected in
|Positive FC detected in
|IF : 1:50-1:500
|This reagent has been tested for flow cytometric analysis. It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
|Sample-dependent, check data in validation data gallery
CL488-65057 targets CD16/32 in IF, FC applications and shows reactivity with Mouse samples.
|Host / Isotype
|Rat / IgG2a, lambda
|VH81X Tg B cells and T220 stromal cell line
|Fc receptor, IgG, low affinity IIb
|GenBank accession number
|Gene ID (NCBI)
|CoraLite® Plus 488 Fluorescent Dye
|Excitation/Emission maxima wavelengths
|493 nm / 522 nm
|PBS with 0.1% sodium azide and 0.5% BSA, pH 7.3.
|Store at 2-8°C. Avoid exposure to light. Stable for one year after shipment.
CD16 (FcγRIII) is a 50-70 kDa low affinity Fc receptor found on the surface of natural killer cells, neutrophil polymorphonuclear leukocytes, monocytes and macrophages. CD16 mediates antibody-dependent cellular cytotoxicity (ADCC) and other antibody-dependent responses, such as phagocytosis. CD32 (FcγRII) is a 40 kD transmembrane glycoprotein that binds to the Fc region of IgG with low affinity. CD32 is present on phagocytic cells such as macrophages and neutrophils, and is involved in the process of phagocytosis and clearing of immune complexes.