Anti-Human CD204 Rabbit Recombinant Antibody

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  FC experiment of human PBMCs using 98398-4-RR

  1x10^6 GM-CSF, IL-4 and IL-10 treated human PBMCs were surface stained with 0.25 ug Anti-Human MSR1/CD204 Rabbit RecAb (98398-4-RR, Clone: 242710D4) (red) or 0.25 ug Rabbit IgG Isotype Control Recombinant Antibody (98136-1-RR, Clone: 240953C9) (blue), and PE-Conjugated Goat Anti-Rabbit IgG(H+L). 1x10^6 untreated human PBMCs were surface stained with 0.25 ug Anti-Human MSR1/CD204 Rabbit RecAb (98398-4-RR, Clone: 242710D4) and PE-Conjugated Goat Anti-Rabbit IgG(H+L) (black, dashed). Cells were not fixed.

CD204 Uni-rAb^® Recombinant Antibody for FC

Cat No. 98398-4-RR

Clone No.242710D4

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

FC

Synonyms

Macrophage acetylated LDL receptor I and II, Macrophage scavenger receptor types I and II, MSR1, SCARA1, Scavenger receptor class A member 1

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Tested Applications

• Positive FC detected in: GM-CSF, IL-4 and IL-10 treated human PBMCs

Recommended dilution

• Flow Cytometry (FC): FC : 0.25 ug per 10^6 cells in a 100 µl suspension

This reagent has been tested for flow cytometric analysis. It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Sample-dependent, Check data in validation data gallery.

Product Information

98398-4-RR targets CD204 in FC applications and shows reactivity with human samples.

• Tested Reactivity: human
• Host / Isotype: Rabbit / IgG
• Class: Recombinant
• Type: Antibody
• Immunogen:

  CatNo: Eg2566

  Product name: Recombinant Human CD204 protein (rFc Tag)

  Source: mammalian cells-derived, pHZ-KIsec-N-rFc

  Tag: N-rFc

  Domain: 77-451 aa of BC063878

  Sequence: KWETKNCSVSSTNANDITQSLTGKGNDSEEEMRFQEVFMEHMSNMEKRIQHILDMEANLMDTEHFQNFSMTTDQRFNDILLQLSTLFSSVQGHGNAIDEISKSLISLNTTLLDLQLNIENLNGKIQENTFKQQEEISKLEERVYNVSAEIMAMKEEQVHLEQEIKGEVKVLNNITNDLRLKDWEHSQTLRNITLIQGPPGPPGEKGDRGPTGESGPRGFPGPIGPPGLKGDRGAIGFPGSRGLPGYAGRPGNSGPKGQKGEKGSGNTLTPFTKVRLVGGSGPHEGRVEILHSGQWGTICDDRWEVRVGQVVCRSLGYPGVQAVHKAAHFGQGTGPIWLNEVFCFGRESSIEECKIRQWGTRACSHSEDAGVTCTL

• Full Name: macrophage scavenger receptor 1
• Calculated Molecular Weight: 451 aa, 50 kDa
• GenBank Accession Number: BC063878
• Gene Symbol: MSR1
• Gene ID (NCBI): 4481
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Protein A purification
• UNIPROT ID: P21757
• Storage Buffer: PBS with 0.09% sodium azide, pH 7.3.
• Storage Conditions: Store at 2 - 8°C. Stable for one year after shipment.

Background Information

MSR1, also known as scavenger receptor-A (SR-A) or cluster of differentiation 204 (CD204), was first described in 1979 by Brown and Goldstein. MSR1 is highly expressed in lung, arteries, and adipose tissue.MSR1 is predominantly expressed in various macrophage cell types and is mainly altered in macrophage-associated physiological and pathological processes including atherosclerosis, Alzheimer's disease, host defence, and cancer.