|Positive WB detected in||human placenta tissue|
|Positive FC detected in||U-937 cells|
|Western Blot (WB)||WB : 1:500-1:2400|
|Sample-dependent, check data in validation data gallery|
The immunogen of 25404-1-AP is CD209 Fusion Protein expressed in E. coli.
|Host / Isotype||Rabbit / IgG|
|Immunogen||CD209 fusion protein Ag21863|
|Full Name||CD209 molecule|
|Calculated molecular weight||404 aa, 45.7 kDa|
|Observed molecular weight||45 kDa|
|GenBank accession number||BC110615|
|Gene ID (NCBI)||30835|
|Purification Method||Antigen affinity purification|
|Storage Buffer||PBS with 0.02% sodium azide and 50% glycerol pH 7.3.|
|Storage Conditions||Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.|
CD209 (DC-SIGN, CLEC4L) is a C-type lectin receptor that is involved in the innate immune system and recognizes numerous evolutionarily divergent pathogens, including bacteria, viruses, and parasites. CD209 is preferentially expressed on dendritic cells (DCs). It mediates transient adhesion of DCs with T cells. It has been reported that CD209 plays a role in capture and transmission of HIV from DC to T cells (PMID: 10721995).