CoraLite® Plus 647 Anti-Human CD27 (O323)
CD27 Monoclonal Antibody for FC
Host / Isotype
Mouse / IgG1, kappa
CoraLite® Plus 647 Fluorescent Dye
Cat no : CL647-65132
|Positive FC detected in
|human peripheral blood lymphocytes
|This reagent has been pre-titrated and tested for flow cytometric analysis. The suggested use of this reagent is 5 µl per 10^6 cells in a 100 µl suspension or 5 µl per 100 µl of whole blood.
|Sample-dependent, check data in validation data gallery
CL647-65132 targets CD27 in FC applications and shows reactivity with Human samples.
|Host / Isotype
|Mouse / IgG1, kappa
|Calculated molecular weight
|GenBank accession number
|Gene ID (NCBI)
|CoraLite® Plus 647 Fluorescent Dye
|Excitation/Emission maxima wavelengths
|654 nm / 674 nm
|PBS with 0.1% sodium azide and 0.5% BSA, pH 7.3.
|Store at 2-8°C. Avoid exposure to light. Stable for one year after shipment.
CD27 (also known as TNFRSF7) is a type I glycoprotein expressed on some B cells and the majority of T cells, and is a member of the tumor necrosis factor (TNF) receptor family. CD27 is required for generation and long-term maintenance of T cell immunity (PMID: 11062504). It is a receptor for CD70 (CD27L). Ligation of CD27 by CD70 induces strong ubiquitination of TRAF and the activation of both canonical and non-canonical NF-kappaB pathways, as well as the JNK pathway (PMID: 19426224). CD27 may also play a role in apoptosis through association with SIVA1.