|Positive FC detected in
|This reagent has been tested for flow cytometric analysis. It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
|Sample-dependent, check data in validation data gallery
FITC-65060 targets CD3ε in FC applications and shows reactivity with Mouse samples.
|Host / Isotype
|Hamster / IgG
|H-2Kb-specific murine cytotoxic T-lymphocyte (CTL) clone BM10-37
|CD3 antigen, epsilon polypeptide
|GenBank accession number
|Gene ID (NCBI)
|FITC Plus Fluorescent Dye
|Excitation/Emission maxima wavelengths
|495 nm / 524 nm
|PBS with 0.1% sodium azide.
|Store at 2-8°C. Avoid exposure to light. Stable for one year after shipment.
CD3 is a multimeric protein associated with the T-cell receptor (TCR) to form a complex involved in antigen recognition and signal transduction (PMID: 15885124). CD3 is composed of CD3γ, δ, ε, and ζ chains (PMID: 1826255). It is expressed by thymocytes in a developmentally regulated manner, T cells, and some NK cells (PMID: 3289580). The TCR recognizes antigens bound to major histocompatibility complex (MHC) molecules. TCR-mediated peptide-MHC recognition is transmitted to the CD3 complex, leading to the intracellular signal transduction (PMID: 11985657).
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