CD44 Antibody 3 Publications

Mouse Monoclonal| Catalog number: 60224-1-Ig |CloneNo.: 6F4H2

Featured Product KD/KO validated

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Freight/Packing

Con: 191 μg/150 μl

Choose size:

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Species specificity:
human, pig

Positive WB detected in:
Hela cells, human spleen tissue, pig spleen tissue, HeLa cells , HUVEC cells

Positive IHC detected in:
human lung cancer tissue, human breast cancer tissue, human lung cancer tissue, human tonsillitis tissue

Positive IF detected in:
MCF-7 cells, human lung cancer tissue

Positive FC detected in:
Raji cells

Recommended dilution:
WB : 1:500-1:2000
IHC : 1:50-1:500
IF : 1:10-1:100

Product Information


Source:
Mouse

Purification method:
Protein A purification

Isotype:
IgG2a

Storage:
PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
CD44 molecule (Indian blood group)

Calculated molecular weight:
742aa,82 kDa

Observed molecular weight:
80-95 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
CD44

Synonyms
CD44, CD44 antigen, CDW44, CSPG8, ECMR III, Epican, HCELL, Heparan sulfate proteoglycan, Hermes antigen, HUTCH I, Hyaluronate receptor, IN, LHR, MC56, MDU2, MDU3, MIC4, MUTCH I, PGP 1, PGP I, Pgp1, Phagocytic glycoprotein 1, Phagocytic glycoprotein I
Background

CD44 is a type I transmembrane glycoprotein that mediates cell-cell and cell-matrix interactions through its affinity for hyaluronic acid (HA) and possibly also through its affinity for other ligands. Adhesion with HA plays an important role in cell migration, tumor growth and progression. CD44 is also involved in lymphocyte activation, recirculation and homing, and in hematopoiesis. This protein exists in multiple isoforms (with molecular weight ranging from 16 kDa to over 200 kDa) generated by alternative RNA splicing and undergoes extensive post-translational modifications.


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