CoraLite®594-conjugated CD63 Monoclonal antibody
CD63 Monoclonal Antibody for IF
Host / Isotype
Mouse / IgG1
CoraLite®594 Fluorescent Dye
Cat no : CL594-67605
|Positive IF detected in||human tonsillitis tissue|
|Immunofluorescence (IF)||IF : 1:50-1:500|
|Sample-dependent, check data in validation data gallery|
CL594-67605 targets CD63 in IF applications and shows reactivity with Human samples.
|Host / Isotype||Mouse / IgG1|
|Immunogen||CD63 fusion protein Ag19690|
|Full Name||CD63 molecule|
|Calculated molecular weight||26 kDa|
|Observed molecular weight||35 kDa|
|GenBank accession number||BC002349|
|Gene ID (NCBI)||967|
|Conjugate||CoraLite®594 Fluorescent Dye|
|Excitation/Emission maxima wavelengths||593 nm / 614 nm|
|Purification Method||Protein G purification|
|Storage Buffer||PBS with 50% Glycerol, 0.05% Proclin300, 0.5% BSA, pH 7.3.|
|Storage Conditions||Store at -20°C. Avoid exposure to light. Aliquoting is unnecessary for -20oC storage.|
CD63, known as LAMP-3, is a 30-60 kDa lysosomal membrane protein that belongs to the tetraspanin family. This protein plays many important roles in immuno-physiological functions. It mediate signal transduction events that play a role in the regulation of cell development, activation and motility. CD63 is expressed on activated platelets, thus it may function as a blood platelet activation marker. CD63 is a lysosomal membrane glycoprotein that is translocated to plasma membrane after platelet activation. The CD63 tetraspanin is highly expressed in the early stages of melanoma and decreases in advanced lesions, suggesting it as a possible suppressor of tumor progression. Deficiency of this protein is associated with Hermansky-Pudlak syndrome.
The reviews below have been submitted by verified Proteintech customers who received an incentive forproviding their feedback.
Amr (Verified Customer) (10-07-2021)
Anti CD63 CL488 and CL594 were validated in Blood plasma exosomes and in bone marrow. The antibodies seem to recogize their specific epitopes very well both extra and intracellularly. Strongly recommended.!